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Comprehensive evaluation including medical history, aesthetic assessment, metabolic panel, biomarker analysis, and establishment of personalized treatment protocols

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The HA-enriched outer layers maintain hydration, modulate immune responses, and support epithelial migration, while GSH-loaded inner cores buffer ROS accumulation and sustain redox homeostasis [33]

Heterogeneity of satellite cells implicates DELTA1/NOTCH2 signaling in self-renewal