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Conclusion : SAG has more preclinical data supporting liver protection, especially in anti-inflammation and antioxidant pathway activation

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These species can promote malignant changes in the colonic epithelium by inducing inflammation or DNA damage (Pleguezuelos-Manzano et al., 2020

[9] Patients with these disorders frequently experience burning pain of their skin at the start of disease

Several enzymes involved in the glutathione pathway, such as -glutamylcysteine synthetase (GCLC), glutathione synthetase (GSS), glutathione peroxidase 4 (GPX4), and glutathione reductase (GSR), are regulated, at least in part, by Nrf2 through its activation of the Nrf2-antioxidant response element