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On February 22nd, the US Food and Drug Administration (FDA) announced the resulution of a years-long shortage of semaglutide, the key ingredient in popular GLP-1 weight loss and diabetes medications Ozempic amd Wegovy

Then he turned to study the venom of another lizard, Gila monster, to find out whether it had a hormone like that too

Milligrams measure the amount of active medication

Semaglutide, a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist, has seen explosive uptake due to its efficacy in glycemic control, weight loss and cardiometabolic risk reduction, driving multibillion-dollar revenues for originator companies Novo Nordisk (maker of semaglutide products Ozempic and Wegovy) and Eli Lilly (the pharma giant behind the tirzepatide products Mounjaro and Zepbound)

Metabolism 2004;53:488-494