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FIGURE 2 2.2.1 Cellular mechanisms of metabolic reprogramming The core pathological feature of PH is metabolic reprogramming in cells such as PASMCs and PAECs

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For lineage tracing in adult mice, 20-24 week-old Esm1-CreERT2 tg/+ R26-mTmG tg/+ males were injected once with 2 mg 4-OHT in oil i.p

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