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Tirzepatide vs Retatrutide: The Big Differences at a Glance A big difference between these two meds is that tirzepatide is currently available (under the brand names Mounjaro and Zepbound) while retatrutide is still considered an investigational drug, undergoing clinical trials

You might find that youre simply not as hungry as usual, or that you feel satisfied after eating less than you normally would

Get bloodwork every 8 to 12 weeks

The primary outcome of the study was the change in alanine aminotransferase (ALT) levels

These adaptations may explain why metabolic benefits can continue to improve over weeks to months of consistent use, rather than plateauing immediately