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Research demonstrates that IGF-1 LR3 activates the same downstream pathways as native IGF-1, primarily the PI3K/Akt/mTOR and Ras/MAPK/ERK cascades, but with greater potency due to its prolonged receptor availability

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These aren't for human use, of course, but are designed for researchers who are studying synergistic effects between compounds like BPC-157 and TB-500

The compound also stimulates appetite pathway signaling as a downstream ghrelin receptor effect, a research signature that distinguishes it from later GHS peptides like Ipamorelin

This schedule is recommended because Sermorelin is designed with support of the growth hormone-releasing hormone (GHRH) in mind