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The results were life-changing, but when supplies dwindled because of a worldwide shortage, she asked her doctor whether it was safe to use an unofficial version of the drug made at a compounding pharmacy

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Lactate that is produced from an oxygen-independent metabolic pathway (glycolysis) is shuttled to various tissues including muscle, heart, and brain, where it is used as a substrate for oxygen-dependent energy production

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Furthermore, the association was independent of previous adjusted demographic and clinical factors after stepwise forward selection (OR = 1.562, 95%CI = 1.1322.154, p = 0.007)