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The chemical constituents found in bitter hop include humulone, lupulone, xanthohumol and adlupulone

(2024) who revealed 40% refractory reduction but inconsistent with Azzam et al

Effects of berberine on the blood concentration of cyclosporin A in renal transplanted recipients: clinical and pharmacokinetic study

They also report reduction in hospital admissions for HF that was not present in any of the individual trials, and thus should be interpreted with caution given the limitations in statistical design of meta-analyses

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