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We explore how close researchers may be to a cure, including promising gene therapy clinical trials, and what experts say still needs long-term study
Medications and supplements We may recommend options such as: PDE-5 inhibitors Acetyl L-Carnitine L-Arginine Topical Diclofenac (1% Gel) These treatments aim to reduce inflammation, soften plaque, and improve comfort (Restorative Health Clinic, 2025)
Done well, these can restore structure and plump out hollows
Thus, it can reduce the expression of inflammatory factors in the synovium of OA and protect against the breakdown of OA chondrocytes and cartilage degeneration (69, 70)
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Other smaller studies support these findings
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