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Notably, the lysosome plays an important role in cellular iron homeostasis 22 and this lysosomal function has been reported to be involved in reactive oxygen species (ROS) generation and ferroptosis 11

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Not all findings, however, are unanimously optimistic

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10.1007/s12550-016-0265-7 Mycotoxin Res

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Oncol Letters (2016) 11(5):33848

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Uniprot P36969-2) is constituted by a catalytic tetrad that consists of the following residues: selenocysteine (Sec 46 ), glutamine (Gln 81 ), tryptophan (Trp 136 ) and asparagine (Asn 137 ) [35]

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