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In phase 3 trials, maximal dose retatrutide demonstrated 29% placebo-adjusted weight loss at 68 weeks (albeit with higher discontinuation rates than semaglutide and tirzepatide)

Its dual benefits in controlling blood sugar and supporting weight loss make semaglutide a promising option for those seeking improved health outcomes in managing type 2 diabetes and chronic weight-related issues

Severe or unusual nausea, vomiting, or diarrhea that differs from your normal semaglutide experience

You inject it like an EpiPen, and you have your dose

While comprehensive comparative data is not yet available, existing evidence provides some initial guidance