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Discontinuation rates due to AEs: - Placebo: 4.9% - 4 mg: 4.1% - 9 mg: 6.9% - 12 mg: 11.3% The 11.3% discontinuation rate at the highest dose is a number worth watching

Paniagua, J

In contrast, immediate widespread reactions, progressive swelling, difficulty breathing, or systemic symptoms may indicate a more serious hypersensitivity reaction requiring urgent medical evaluation

Please consult your healthcare provider before starting or changing any medication or treatment

Insurance coverage is indeed crucial, but the process of getting insurance companies to cover new drugs can be lengthy and may not guarantee that all patients will have access