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GLP-1 secretion may be impaired in individuals with metabolic health concerns like insulin resistance, or type 2 diabetes

Lancet 372 , 12401250 (2008)

Since the safety and efficacy of such novel therapeutics are a major concern for clinical application, regulatory bodies will require stringent quality checks prior to allowing clinical advancement [261]

But experts say most people notice at least some effects after stopping a GLP-1 medication

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