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Comorbidities were notably more prevalent in the tirzepatide group, particularly overweight and obesity (48.1% vs

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LC conditions: Separation of ceramide species was performed on an Agilent 1200 series HPLC system (Agilent Technologies, Palo Alto, CA) using an Ascentis C18 column (5 cm 2.1 mm I.D., 3 m particle size, Supelco, Bellefonte, PA)

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