Mistaken uracil substitution for thymidine can eventually result in strand breakage, unstable DNA, and defective DNA repair (163)
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Building on these findings, our recent study demonstrated that sulforaphane prevented ASD-associated phenotypes induced by valproic acid, including oxidative stress, synaptic loss and neural activity disruption, highlighting sulforaphanes potential as a preventative strategy against early life ASD risk (Bessetti et al., 2025)