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Research, including recent findings from the SELECT trial, indicates that GLP-1 agonists like semaglutide can significantly reduce the risk of major cardiovascular events, such as heart attacks and strokes, especially in individuals with obesity but without diabetes

Ahrn, B., Masmiquel, L., Kumar, H., Sargin, M., Karsbl, J

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These shifts in metabolism are often global across the brain, e.g., in a meta-analysis, the conditions of eyes closed versus open, sevoflurane and desflurane anesthesia, and comas of varying levels all demonstrated a global shift, whereas only congenitally blind versus sighted demonstrated localized changes [61]