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Its not FDA-approved and is prohibited in elite sport under WADAs S0 category (non-approved substances)

and intelligent biomimetic nanosystems combine uricase degradation, near-infrared hyperthermia, and M2 macrophage membrane targeting to achieve dual interventions in uric acid metabolism regulation and inflammatory repair (Xu et al., 2024)

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Although prolonged treatment with oral N-acetylcysteine (NAC) prevents acute exacerbations of chronic bronchitis, it remains controversial for the treatment of COPD (91, 103105)

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