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Aberrant activation of hippocampal astrocytes causes neuroinflammation and cognitive decline in mice

Its not clear to me what bias this might produce

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Furthermore, analysis of the sequences within 5 kb from the transcription start sites (TSSs) of VEGFA and IL8 using RcisTarget [30] identified enriched motifs for DNA-binding activators (cisbp _ M3992 motif-binding STAT6) both in the TSSs of VEGFA and IL8 (Fig