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Dimercaprol is toxic and may also chelate with toxic metals, which can result in their accumulation in certain organs (e.g., brain and testes) (Flora and Pachauri, 2010)

doi: 10.3109/00365527909179871 25 SarsonDLScopinaroNBloomSR

Statistics and reproducibility The phase 2 clinical trial was powered to show a difference in proportions of 28% on primary endpoint MASH resolution and no worsening of fibrosis between once-daily semaglutide 0.4 mg (assumed 45% response) and placebo (assumed 17% response)