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An analog of alpha-melanocyte-stimulating hormone (-MSH), afamelanotide stimulates the skins production of melanin by activating melanocortin-1 (MC1) receptors

The first of these is the Wegovy Pill, which is now available for pre-order

In a large study involving 12,548 propensity matched type 2 diabetes patients from three U.S.-based insurance claims databases, addition of an SGLT2 inhibitor to background therapy with GLP-1 receptor agonist reduced the composite CV outcome by 24%, myocardial infraction by 29% and all-cause mortality by 32% (Dave CV, et al

None of these are included in the Zealthy membership or medication cost

Adipotide: Strictly targeted at the vascular endothelium (blood vessel lining) of white adipose tissue, entirely ignoring muscle or organ tissue