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Your doctor may suggest you use another form of birth control for 4 weeks after starting tirzepatide and for 4 weeks after each dose change

For the first two weeks, I didn't think it was working and was going to ask for my money back, then it hit me and I started noticing the weight dropping off

doi: 10.1016/j.phrs.2018.03.004 39 LiljedahlL.PedersenM

Clinical Evidence for Semaglutide-Naltrexone Combination The strongest evidence for semaglutide plus naltrexone comes from the IMCOSI phase 2b trial (2021), which enrolled 338 patients and found that the combination resulted in approximately 20% body weight loss over 48 weeks, compared to 16% for semaglutide alonea difference that was statistically significant but modest in absolute terms

These medications, combined with dietary changes, can increase the risk of low B12 levels