Autophagy mediates the process of cellular senescence characterizing bile duct damages in primary biliary cirrhosis
Bak MJ, et.al., Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): implications for GLP-1 measurements in clinical studies
McCord, a biochemist credited with inventing the Protandim compound who went on to serve as the companys lead scientific officer, gave occasional talks to LifeVantage distributors describing how components of the supplements such as plant extracts, like milk thistle or ashwagandha might regulate a biochemical pathway by switching on particular genes
The mechanisms could include reduced inflammation, improved metabolic health, direct effects on brain reward pathways, or the psychological benefit of successful weight management
A phase 3 randomized controlled trial found no significant improvements with the GLP-1 exenatide in this population