Drinking an electrolyte beverage (or adding electrolytes to your water) can make a big difference in how you feel
1 Inadequate protein or micronutrient intake while appetite is suppressed
These include improvement in MASLD-related steatohepatitis and steatosis,155,156 knee pain in osteoarthritis,106 cardiovascular outcomes,99 and potentially substance use disorders.157 Common side effects of GLP-1 agonists include nausea, constipation, diarrhea, vomiting, abdominal discomfort, and reduced appetite.63,67,148,158 Side effects tend to be transient and resolve with time, but impact real-world adherence.159 Patients on GLP-1 receptor agonists do lose muscle mass, as is commonly seen with all forms of weight loss.160 Serious adverse events include gallbladder and biliary disease, which are believed to be dose-related and result from GLP-1 inhibiting gallbladder emptying through CCK suppression.120,140 Contraindications to use of GLP-1 receptor agonists include medullary thyroid carcinoma, family history of MEN type 2 syndrome, pancreatitis, and relative contraindications include diabetic retinopathy and uncontrolled diabetes.161,162 Given the recent approvals of these anti-obesity medications, providers and patients are undoubtedly concerned about what long-term safety data is available
This is a question worth asking Omzo's support team directly before enrolling, particularly given the pending regulatory action
What women with PCOS reported 74% noticed changes in cycle regularity 43% noticed changes in cycle predictability 57.5% reported changes in PCOS-related symptoms What this suggests GLP-1 medications are increasingly discussed in the context of PCOS particularly due to links with insulin resistance
