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Int J Mol Sci 24(4):3207 Wang Y, Wu L, Fu J, Lv H, Guan X, Xu L, Chen P, Gao C, Hou P, Ji M (2013) Hyperthyroid monkeys: a nonhuman primate model of experimental Graves disease
They genetically incorporated the latent bioactive ncAA, fluorosulfate-L-tyrosine (FSY) 268 , into human programmed cell death protein 1 (PD-1) at position 129 and showed that the resulting PD-1(FSY) formed covalent bonds selectively with its natural ligand, PD-L1, in vitro and in vivo