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Their further research showed (127) that GCK could inhibit the abnormal activation and differentiation of T cells in CIA and AIA animal models, and its potential molecular mechanism might be the inhibition of CCL21/CCR7-mediated DC migration and signal transduction between T cells and DC

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The C-terminal ~10 amino acids of CT-family peptides, including CT, rAmy, and Cagri, bind to the same groove within the ECD of their cognate receptors (Fig

Oncotarget 6 , 41264143 (2015)