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The primary aim was to determine AOD9604s impact on body weight, adipose tissue mass, gene expression of 3-AR, and metabolic activity, as well as to evaluate whether the 3-AR is required for its effects [2]

Assessment at the four-week mark helps determine whether dose adjustment is needed

The compounds were intraperitoneally administered with the compound at 8 a.m

The compounds give researchers options to study different cellular pathways, allowing for more comprehensive studies that can give us a better understanding of metabolic mechanisms

These nuclear receptors act as transcription factors rather than membrane receptors