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Despite the above, semaglutide should now be considered as a key protective agent for most people with T2D and CKD as it reduces the risk of clinically import kidney and CV outcomes and also improves multiple metabolic parameters

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Even though these conditions look different and have different causes, they seem to share some common underlying problems, including neuroinflammation, trouble with mitochondria, oxidative stress, and programmed cell death

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When examining the individual components of the primary endpoint, we observed closely concordant results for myocardial infarction and stroke but divergent results for all-cause mortality, suggestive of residual confounding