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Side Effects of Wellbutrin Common: headache, dry mouth, nausea, insomnia, sore throat, taste changes, constipation, increased sweating, weight changes Serious: seizure risk (dosedependent), high blood pressure, suicidal thoughts (especially under age 24), allergic reactions, mania or hypomania, worsening glaucoma, sexual dysfunction (lower risk than other antidepressants) Precautions Before Starting Wellbutrin Inform your provider about any of the following: History of seizures or eating disorders Head injury or central nervous system tumors Glaucoma Heart disease or high blood pressure Diabetes or bipolar disorder Alcohol or substance use history Kidney or liver disease Pregnancy or breastfeeding plans Sources Anderson JW et al