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A clear band at approximately 30% sucrose concentration was observed, extracted and the presence of EV-F3 was confirmed by SDS-Page gel electrophoresis

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The function of EAAC1 is also promoted by the mammalian target of rapamycin (mTOR) [69] and Janus-activated tyrosine kinase-2 (JAK-2) [70], which are involved in cell growth, differentiation, and proliferation

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These metabolic studies jointly suggest that wtIDH1 enhances antioxidant defense through the generation of NADPH and impacts metabolic pathways at the level of the TCA cycle through the generation of IDH1-derived KG