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Sitagliptin demonstrates selectivity for DPP-4 and does not inhibit DPP-8 or DPP-9 activity in vitro at concentrations approximating those from therapeutic doses
& McLachlan, S.M
Indeed, CCK has moved from being considered a local gut hormone, to being recognized as an almost ubiquitous chemical messenger (122)
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Although meta-regression revealed that the proportion of male patients was not associated with the source of heterogeneity in AHI outcome, it may be beneficial for future studies to include sufficient female participants and consider reporting treatment outcomes separately for male and female patients
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