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This exercise-induced oxidative stress can temporarily deplete glutathione as the antioxidant system works to neutralize the increased free radical production

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They can therefore be injured by a variety of pro-inflammatory and pro-fibrotic substances that cause tubular injury

Cook et al., 1994

Leucovorin (Folinic Acid) and Autism What it is: Leucovorin (folinic acid) is a reduced form of folate that bypasses certain metabolic blocks, including folate receptor autoantibodies (FRAA), that are more commonly seen in children with neurodevelopmental concerns including autism and PANS/PANDAS