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Excess fat accumulation, particularly visceral fat around organs, promotes chronic inflammation, insulin resistance, and dyslipidemia (abnormal blood lipid levels)

We need prospective studies that stratify GLP-1 agonist outcomes by baseline endogenous hormone levels, something no major clinical trial has done

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Doi: 10.1186/s12906-023-04077-7

Once you stop, your body's appetite signals bounce backnot because you've failed, but because semaglutide's neurological effects fade