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The down-regulation of Nrf2 genes results in a decrease in antioxidant defense is due to the decreased expression of Nrf2-related antioxidant genes and thus, the oxidative stress induced by OTA may account for both the genetic damage and the cytotoxicy related to OTA [79]

Cell Metab 2008

Impact of age-related genetic differences on the therapeutic outcome of papillary thyroid cancer

, 2011) periodically to determine the oxygen consumption rate: oxygen measurements were made every day for the assays containing IDYs, sulfur dioxide and glutathione over two weeks, and every hour for the assay containing ascorbic acid over one day

doi:10.1002/j.1875-9114.1983.tb03274.x Valacyclovir (oral route)