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Soluble autoimmunity markers B lymphocyte activating factor (BAFF) has been identified in many autoimmune diseases (519) as it regulates survival and maturation of B cells to control the IL-10 production of regulatory B cells (520, 521)

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While not first-line therapies, both drug classes show promise as adjuncts in high-risk populations

Retatrutides triple-receptor agonismmainly the inclusion of the glucagon receptorprovides a superior metabolic advantage in clearing liver fat and increasing thermogenesis compared to dual agonists