HGH stimulates the liver to produce endogenous IGF-1, whereas IGF-1 LR3 bypasses the liver and acts directly on tissues, making it faster-acting and more targeted in its effects
These intertwined pathways, oxidative stress, low-grade inflammation and neuroimmune-driven sensitisation represent biologically plausible targets for modulation by phytonutrient-rich dietary patterns and specific bioactive compounds [3,17,18,19,25,26,27,28,29,30]
If you have been at a dose that previously produced noticeable appetite suppression and that effect suddenly disappears, potency loss is a possible explanation
Severe allergic reactions, persistent edema, or signs of high IGF-1 (joint pain, carpal tunnel, headaches) warrant clinical review
Labs are repeated at 812 weeks to objectively measure hormonal and metabolic changes