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Calabrese, V., Giuffrida Stella, A

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or fatigability in adulthood (34, 35)

doi:10.1016/j.numecd.2014.03.007

Without targeted interventions to restore mitochondrial transport pathways and quench this raging oxidative fire, patients remain trapped in a devastating state of chronic cellular depletion and systemic hyper-reactivity, unable to break the cycle of fatigue and inflammation