NDA submission expected Q4 2026
However, IDPs exhibit characteristic values of specific heat capacity C p , which are elevated at all temperatures due to greater solvent-exposed surface area, and which exceed the C p values of folded proteins, and in the case of extensively disordered proteins, reaching the values characteristic for fully unfolded protein (Privalov and Makhatadze, 1990)
10.1007/s11357-017-9958-x Geroscience 30 GuZ.ZhaoH.SongY.KouY.YangW.LiY.et al (2024)
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Heerspink HJL, Stefansson BV, Correa-Rotter R, Chertow GM, Greene T, Hou FF, et al