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As a dual GIP and GLP-1 receptor agonist approved for type 2 diabetes and weight management, tirzepatide acts on receptors throughout the central nervous system, influencing appetite regulation and potentially offering neuroprotective properties

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While motor and cognitive outcomes did not differ significantly from placebo, there was a notable improvement in total NMSS scores, and activities of daily living improved significantly as reflected in MDS-UPDRS Part II scores [57]

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