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For both Most Studied Pathways and Gene-Associated Pathways, the threshold of rank 30 was chosen to balance sensitivity and specificity, capturing pathways with substantial evidence while minimizing the inclusion of less relevant ones
Thus, ferroptosis exacerbates intestinal barrier dysfunction and aggravates UC progression, whereas the intervention of SAC against ferroptosis is beneficial for promoting the healing of the intestinal mucosal barrier
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10.3389/fpls.2014.00750 Front
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