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Notably, mitochondrial dysfunction, a hallmark of senescent chondrocytes in OA, induces intracellular ROS production that causes oxidative stress

Observational clinical studies have shown that patients with autoimmune thyroid diseases have lower serum vitamin D levels than healthy controls [62, 103, 104]

3.2 Cuproptosis in OSCC: from tumor suppression to immune landscape shaping Although research on cuproptosis in OSCC is still nascent, accumulating evidence underscores its pivotal role in regulating core malignant behaviors of OSCC cells, such as proliferation, apoptosis, migration, and invasion

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