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AD has a multifactorial origin, and one of the hallmarks of this disease involves the deposition of toxic senile plaques of amyloid- peptides in the brain

Clinical studies suggest that GLP-1 analogs can mitigate symptoms in patients with Crohns Disease and Ulcerative Colitis by reducing macrophage activation and restoring epithelial integrity (Cani et al., 2016)

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The commercial success of any weight loss therapeutic will depend heavily on patient acceptability and adherence, making oral, long-acting depot, and other non-injectable options critical pipeline priorities rather than nice-to-have features