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Larger metabolite panels also improve the understanding of biological complexity, revealing novel associations and fluxes between biochemical pathways [60]

Researchers included 1442 breast cancer patients in our cohort analysis, with 710 serving as the test population and 732 as the control, in Switzerland and Germany

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Several of these metabolites have anticancer activities by modulating ERK1/2 phosphorylation [132] and microtubule function [132,133] although their biological actions have not been well studied

Modest reductions in LDL-cholesterol, total cholesterol, and triglycerides are also observed in patients receiving GLP-1RAs when compared with other antidiabetic agents [84]