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How AOMs Work in the Body The contemporary AOMs receiving heightened attention are referred to as nutrient-stimulated hormone (NuSH) therapies

Ceda, G.P., et al

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This non-peptide mechanism, elucidated through cryo-electron microscopy and published in the Proceedings of the National Academy of Sciences in 2020, overturned decades of pharmacological dogma that class B GPCRs could only be meaningfully activated by peptide ligands

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