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It is used in addition to diet and exercise for long-term weight management in: Adults with obesity and adults with overweight and with at least one other weight-related medical issue, like high cholesterol or high blood pressure (injection and pill)

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Peer review Peer review information Nature Communications thanks Weiqin Chen, Neil Kaplowitz, Hozumi Motohashi and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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