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Common reasons include contraindications (medical conditions that make Ozempic unsafe), not meeting eligibility criteria (BMI too low, no qualifying conditions), need for additional testing before making a decision, preference for trying other treatments first, and providers personal practice patterns (some prefer not prescribing GLP-1s)

The full patent stack is likely to extend effective exclusivity into the late 2030s

Sleep disruptions Some people on GLP-1 medications report changes in sleep patterns, especially when first starting treatment

References Chao, A

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