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Kovalzon and Strekalova, summarizing the field in 2006, were explicit: the link between DSIP and sleep had never been further characterized, in part because of the lack of isolation of the DSIP gene, protein and possible related receptor, and the hypothesis of DSIP as a sleep factor was extremely poorly documented and still weak (Kovalzon & Strekalova, 2006)

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Glutathione as an endogenous sulfur source in the yeast Saccharomyces cerevisiae

Peptides like Ipamorelin, while not directly neuroprotective, support growth hormone secretion that influences brain repair indirectly

DSIP appears to play roles in stress response, pain modulation, hormonal regulation, and withdrawal from addictive substances