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Neelakantan, H., Vance, V., Wetzel, M

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In tumor cells, lysine uptake is facilitated through membrane receptors such as SLC7A1, SLC7A2, and SLC7A3, with SLC7A2 being the predominant transporter [37]

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In a study led by Marathe et al., retatrutide-induced weight loss reduced tumor engraftment, delayed tumor onset, and significantly attenuated tumor growth in pancreatic and lung cancer models, with greater tumor suppression than the GLP-1 receptor agonist semaglutide