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Values above the solid line connecting 200 mcg/mL at least 4 hours with 50 mcg/mL at 12 hours are associated with a possibility of hepatic toxicity if an antidote is not administered
124(Pt A):110825 (2023)
Contraindications Orlistat is contraindicated in patients with: Chronic malabsorption syndrome Cholestasis (blocked bile flow from the liver) Known hypersensitivity to orlistat or any component of the formulation Pregnancy and breastfeeding Monitoring and Duration of Use Treatment with orlistat should be discontinued after 12 weeks if a patient has not lost at least 5% of their initial body weight
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(2) Ernest Adeghate and Abdul Samad Ponery (2004) Mechanism of ipamorelin-evoked insulin release from the pancreas of normal and diabetic rats Neuro Endocrinology Letters, 2004 Dec, Volume 25 (Issue 6), Pages 403-6
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