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CMAJ: Canadian Medical Association Journal, 196 (43), E1413

Significant weight loss from any cause can reduce bone mineral density, and muscle mass is directly correlated with bone health

Second, the Hims advertisement violates your specific Guidelines for weight loss/control products. Those Guidelines require all [c]laims for weight loss products or programs to be substantiated and to be advertised in the context of an overall healthy program that includes an exercise regimen, a reduction in caloric intake and proper nutrition. Hims advertisement falls well short of this requirement too

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Currently, orlistat is a commonly prescribed weight-loss medication in the UK, licensed for adults with a BMI 30 kg/m, or 28 kg/m with risk factors