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In a phase 2, randomized, double-blind, placebo-controlled trial (NCT05669599) of adults with obesity (with and without type 2 diabetes), once-monthly MariTide produced dose-dependent reductions in body weight of up to 16% at 52 weeks, compared with approximately 2% to 3% with placebo

A 2012 paper in Oxidative Medicine and Cellular Longevity confirmed that GHK-Cus biological activity depends on proper copper complexation

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The body produces GH in pulses, with the largest pulse occurring during deep sleep

Biochem Biophys Acta 710(2):197211